Shadowbox is a cross-browser, cross-platform Lightbox-like media viewer which supports all the commonly used media types like images, QuickTime, Windows Media Player, Flash, Flash video, and even external web pages.

Shadowbox can be used easily with the popular JavaScript frameworks as it already has adapters for jQuery, Prototype + Scriptaculous, Ext.js & Yahoo! User Interface Library.
Flash Video is supported via JW FLV Player. Although many types of video are supported, for compatibilty reasons, Shadowbox advises that Flash Video to be used.
Requirements: No Requirements
Compatibility: All Major Browsers & JavaScript Frameworks
Zenphoto is a php - mysql image & video gallery script which has all the features an image gallery must have. It is built with simplicity in mind, this makes Zenphoto is a very easy to use gallery script both for users & admins.
Some features of Zenphoto:
- Image & video albums + sub-albums
- Ftp or admin panel uploading of images, videos
- Commenting
- Tags
- RSS feed
- Powerful search
- Plugins support (Wordpress plugins, Facebook integration & more)
- Themes support

Zenphoto has an active user community where support can be found for this nice php mysql image & video gallery script.
Requirements: PHP 4.10+ with GD support, MySQL 3.23+
As there are very nice flash & ajax image galleries, this flash gallery application is a bit different from the others as the galleries are created from a desktop application and then uploaded to your website.
Slideroll Gallery AV (formerly Picklish), is a flash image & video gallery tool that lets you create your galleries from a simple drag and drop interface. PC users can also record their own narration with their galleries.
Snarf photos feature of Slideroll Gallery AV lets you to download any images from a website or a rss feed directly into your gallery.

Look and feel of the galleries can be customized and after uploading the image & video gallery to your website, html editing is possible for any tweakings needed.
Compatibility: Windows & Mac OS X
Videobox is a 6kb script, which shows your videos in the page with an overlay. It was inspired from Lightbox.v2 and uses some of the Slimbox’s code. It’s written for the wonderful mootools library. And used swfobject to embed flash.

Requirements: No Requirements